Ceramides (NP, AP, EOP)
Glycolic Acid (AHA)
How to Layer These Actives in Your Routine
Glycolic Acid (AHA)
Apply first to clean, dry skin. Operates at pH 3.2–3.8.
Allows cutaneous acid mantle to equilibrate before the next step.
Ceramides (NP, AP, EOP)
Layer over the initial active. Operates at pH 5–6.5.
Biochemical Mechanism & Pharmacology
Ceramides (NP, AP, EOP) provides vital physiological lipids and humectants that reinforce the stratum corneum lipid matrix, preventing trans-epidermal water loss (TEWL) and buffering against irritation from Glycolic Acid (AHA) without attenuating its therapeutic cellular benefits.
Apply the lower viscosity product first, or buffer by applying Ceramides (NP, AP, EOP) prior to Glycolic Acid (AHA) for sensitive skin (the sandwich method).
Recommended 7-Day Routine Blueprint
| Morning (AM) Routine | Evening (Night A) | Evening (Night B) |
|---|---|---|
✓Gentle Cleanser ✓Ceramides (NP, AP, EOP) ✓Broad-Spectrum SPF 50+ | •Glycolic Acid (AHA) •Ceramides (NP, AP, EOP) •Barrier Seal | •Glycolic Acid (AHA) •Ceramides (NP, AP, EOP) •Barrier Seal |
Obstetric & Pregnancy Safety Summary
View Full Pregnancy Directory →Ceramides (NP, AP, EOP) is classified as PERMITTED during pregnancy, while Glycolic Acid (AHA) is classified as CAUTION LOW DOSE under clinical guidelines. Always cross-reference with your physician if expecting.