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The Ingredients Directory.

Miko tracks 58 active ingredients across 14 chemistry families. Every active carries its dedicated color token — because color is information, not decoration.

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Active Ingredients Directory

Every molecule decoded with clinical mechanisms, pH bounds, and routine placement

60 Actives Catalogued

Cell Turnover / Retinoids

7 Actives

Direct Acids & Exfoliants

8 Actives
Glycolic Acid (AHA)PM Slot

Glycolic Acid (AHA)

The smallest molecular weight alpha-hydroxy acid (76 Da), penetrating deeply to loosen stratum corneum cohesion.

Optimal pH: 3.2 – 3.8
Aliases: 2Monograph →
Lactic Acid (AHA)PM Slot

Lactic Acid (AHA)

A gentle 90 Da alpha-hydroxy acid with inherent humectant properties that exfoliates while restoring Natural Moisturizing Factor.

Optimal pH: 3.5 – 4.0
Aliases: 2Monograph →
Salicylic Acid (BHA)PM Slot

Salicylic Acid (BHA)

A lipid-soluble beta-hydroxy acid capable of penetrating through sebum into follicular pore linings to clear comedones.

Optimal pH: 3.0 – 4.0
Aliases: 3Monograph →
Mandelic Acid (AHA)PM Slot

Mandelic Acid (AHA)

A large 152 Da aromatic alpha-hydroxy acid with gentle penetration kinetics and natural antimicrobial properties.

Optimal pH: 3.5 – 4.2
Aliases: 2Monograph →
Gluconolactone (PHA)AM/PM Slot

Gluconolactone (PHA)

A multi-hydroxy polyhydroxy acid (PHA) that provides gentle micro-exfoliation while shielding against UV-induced free radicals.

Optimal pH: 3.8 – 4.5
Aliases: 2Monograph →
Lactobionic Acid (Bionic Acid)AM/PM Slot

Lactobionic Acid (Bionic Acid)

A third-generation bionic acid composed of gluconic acid and galactose, functioning as a powerful gel-forming antioxidant matrix.

Optimal pH: 3.8 – 4.5
Aliases: 2Monograph →
Benzoyl PeroxideAM/PM Slot

Benzoyl Peroxide

A fast-acting lipophilic oxidizing agent that introduces reactive oxygen into pores to kill anaerobic Cutibacterium acnes bacteria.

Optimal pH: 5.0 – 6.5
Aliases: 1Monograph →
Betaine SalicylateAM/PM Slot

Betaine Salicylate

A gentle equimolar combination of salicylic acid and sugar-beet betaine, popular in Korean skincare as a buffered BHA.

Optimal pH: 4.0 – 4.8
Aliases: 1Monograph →

Direct Antioxidants

7 Actives
L-Ascorbic Acid (Pure Vitamin C)AM Slot

L-Ascorbic Acid (Pure Vitamin C)

The gold-standard biological antioxidant that scavenges reactive oxygen species and serves as an essential cofactor for collagen synthesis.

Optimal pH: 2.8 – 3.5
Aliases: 2Monograph →
3-O-Ethyl Ascorbic AcidAM/PM Slot

3-O-Ethyl Ascorbic Acid

An etherified, amphiphilic vitamin C derivative that retains high oxidative stability across a broad physiological pH range.

Optimal pH: 4.0 – 5.5
Aliases: 2Monograph →
Tetrahexyldecyl Ascorbate (THD)AM/PM Slot

Tetrahexyldecyl Ascorbate (THD)

An oil-soluble tetra-ester of ascorbic acid that integrates seamlessly into skin lipid lamellae for deep dermal penetration.

Optimal pH: 5.0 – 6.5
Aliases: 2Monograph →
Ascorbyl GlucosideAM/PM Slot

Ascorbyl Glucoside

A water-soluble glucose-stabilized vitamin C that releases active ascorbic acid continuously via alpha-glucosidase enzymes.

Optimal pH: 5.5 – 7.0
Aliases: 2Monograph →
Sodium Ascorbyl Phosphate (SAP)AM/PM Slot

Sodium Ascorbyl Phosphate (SAP)

A stable water-soluble salt of vitamin C clinically proven to inhibit squalene oxidation and suppress C. acnes proliferation.

Optimal pH: 6.0 – 7.0
Aliases: 2Monograph →
Ferulic AcidAM Slot

Ferulic Acid

A plant-derived hydroxycinnamic acid that doubles the photoprotective and chemical stability of vitamins C and E.

Optimal pH: 3.0 – 4.0
Aliases: 1Monograph →
ResveratrolPM Slot

Resveratrol

A potent phytoalexin polyphenol that stimulates endogenous cellular antioxidant enzymes including superoxide dismutase.

Optimal pH: 5.0 – 6.5
Aliases: 2Monograph →

Lipid Barrier Replenishment

5 Actives

Osmolytes & Humectants

6 Actives

Signaling Peptides & Matrikines

4 Actives

Barrier Cofactors & Brighteners

9 Actives
Niacinamide (Vitamin B3)AM/PM Slot

Niacinamide (Vitamin B3)

A water-soluble B3 amide essential for cellular energy metabolism (NAD+/NADP+), sebum regulation, and ceramide synthesis.

Optimal pH: 5.0 – 7.0
Aliases: 2Monograph →
Azelaic Acid (10%–15%)AM/PM Slot

Azelaic Acid (10%–15%)

A multifunctional naturally occurring dicarboxylic acid with comedolytic, antibacterial, and selective tyrosinase-inhibiting properties.

Optimal pH: 4.0 – 5.5
Aliases: 1Monograph →
Potassium Azeloyl Diglycinate (PAD)AM/PM Slot

Potassium Azeloyl Diglycinate (PAD)

A water-soluble azelaic acid derivative synthesized with glycine, providing superior sebum normalization in ultra-lightweight serums.

Optimal pH: 5.5 – 7.0
Aliases: 2Monograph →
Tranexamic Acid (Topical)AM/PM Slot

Tranexamic Acid (Topical)

A synthetic amino acid lysine analog that interrupts communication between melanocytes and keratinocytes triggered by UV damage.

Optimal pH: 5.0 – 6.5
Aliases: 1Monograph →
Alpha-ArbutinAM/PM Slot

Alpha-Arbutin

A naturally occurring glucopyranoside that exerts competitive, reversible inhibition on tyrosinase without cytotoxicity.

Optimal pH: 4.5 – 6.5
Aliases: 2Monograph →
Kojic AcidPM Slot

Kojic Acid

A fungal metabolite produced during koji fermentation that chelates the essential copper atom in tyrosinase.

Optimal pH: 4.0 – 5.5
Aliases: 2Monograph →
Licorice Root Extract (Glabridin)AM/PM Slot

Licorice Root Extract (Glabridin)

A botanical extract rich in glabridin and licochalcone A that inhibits tyrosinase while scavenging superoxide free radicals.

Optimal pH: 4.5 – 6.5
Aliases: 2Monograph →
Hydroquinone (2%–4%)PM Slot

Hydroquinone (2%–4%)

The historical gold-standard prescription tyrosinase competitor that exerts selective cytotoxicity on active melanocytes.

Optimal pH: 4.0 – 5.0
Aliases: 1Monograph →
Zinc PCAAM/PM Slot

Zinc PCA

A physiological zinc salt of pyrrolidone carboxylic acid that down-regulates 5-alpha reductase to control excessive midday sebum.

Optimal pH: 5.0 – 6.5
Aliases: 1Monograph →

Anti-Erythema & Extremolytes

6 Actives

Mineral UV Photoprotection

2 Actives

Organic UV Filters

3 Actives

Volatile Terpenes & Allergens

3 Actives

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