Panthenol (Provitamin B5)
Salicylic Acid (BHA)
How to Layer These Actives in Your Routine
Salicylic Acid (BHA)
Apply first to clean, dry skin. Operates at pH 3–4.
Allows cutaneous acid mantle to equilibrate before the next step.
Panthenol (Provitamin B5)
Layer over the initial active. Operates at pH 5–6.5.
Biochemical Mechanism & Pharmacology
Panthenol (Provitamin B5) provides vital physiological lipids and humectants that reinforce the stratum corneum lipid matrix, preventing trans-epidermal water loss (TEWL) and buffering against irritation from Salicylic Acid (BHA) without attenuating its therapeutic cellular benefits.
Apply the lower viscosity product first, or buffer by applying Panthenol (Provitamin B5) prior to Salicylic Acid (BHA) for sensitive skin (the sandwich method).
Recommended 7-Day Routine Blueprint
| Morning (AM) Routine | Evening (Night A) | Evening (Night B) |
|---|---|---|
✓Gentle Cleanser ✓Panthenol (Provitamin B5) ✓Broad-Spectrum SPF 50+ | •Salicylic Acid (BHA) •Panthenol (Provitamin B5) •Barrier Seal | •Salicylic Acid (BHA) •Panthenol (Provitamin B5) •Barrier Seal |
Obstetric & Pregnancy Safety Summary
View Full Pregnancy Directory →Panthenol (Provitamin B5) is classified as PERMITTED during pregnancy, while Salicylic Acid (BHA) is classified as CAUTION LOW DOSE under clinical guidelines. Always cross-reference with your physician if expecting.