← Back to Ingredients Directory
Direct Acids & ExfoliantsRecommended: AM/PM Slot

Gluconolactone (PHA)

Clinical Overview

A multi-hydroxy polyhydroxy acid (PHA) that provides gentle micro-exfoliation while shielding against UV-induced free radicals.

Epidermal & Cutaneous Mechanism

Bulky molecular size (178 Da) prevents deep penetration, acting strictly on the skin surface with multiple water-attracting hydroxyl groups.

Addresses Skin Concerns
Barrier-compromised rough skinStinging intolerance to AHAsEnvironmental oxidative stress
Recognized INCI Names on Packaging Labels
GluconolactonePolyhydroxy Acid
Compatible Synergies
  • ✓All active ingredients (exceptionally well-tolerated)
Separate or Alternate
  • No significant contraindications documented.