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Cell Turnover / RetinoidsRecommended: PM Slot
Hydroxypinacolone Retinoate (HPR)
Clinical Overview
An advanced retinoic acid ester that directly binds retinoid receptors with drastically reduced cutaneous irritation.
Epidermal & Cutaneous Mechanism
The pinacol ester binds retinoic acid receptors directly without requiring cellular enzymatic cleavage, bypassing epidermal inflammation pathways.
Addresses Skin Concerns
Sensitive skin agingTexture roughnessMild hyperpigmentation
Recognized INCI Names on Packaging Labels
Hydroxypinacolone RetinoateGranactive Retinoid
Compatible Synergies
- ✓Niacinamide
- ✓Peptides
- ✓Ceramide complexes
Separate or Alternate
- ⚠️Strong unbuffered chemical exfoliants