← Back to Ingredients Directory
Signaling Peptides & MatrikinesRecommended: AM/PM Slot
Palmitoyl Pentapeptide-4 (Matrixyl)
Clinical Overview
The classic procollagen peptide fragment (KTTKS) linked to palmitic acid for enhanced cutaneous bioavailability.
Epidermal & Cutaneous Mechanism
Stimulates collagen I and fibronectin synthesis directly in dermal fibroblast cultures without inciting inflammatory reactions.
Addresses Skin Concerns
Loss of dermal thicknessCrepey skin textureFine rhytids
Recognized INCI Names on Packaging Labels
Palmitoyl Pentapeptide-4Matrixyl
Compatible Synergies
- ✓Ceramides
- ✓Niacinamide
Separate or Alternate
- ⚠️Strong unbuffered low-pH solutions