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Permitted · Soothing Anti-Inflammatory

Can you use Centella Asiatica & Madecassoside during pregnancy?

⚠️Medical Deferral Notice

Permitted for topical cosmetic application. Avoid oral herbal preparations without medical clearance. Cosmetic classifications are formulation flags to discuss with your healthcare provider, not medical clearance.

Clinical Summary

A medicinal herbaceous plant that down-regulates pro-inflammatory cytokines and accelerates micro-wound healing.

Pharmacological Mechanism & Teratogenic Context

Madecassoside and asiaticoside suppress NF-kB activation, reducing cutaneous interleukin release (IL-1alpha, IL-6). Topical formulations soothe facial erythema, reactive flushing, and postpartum pruritus safely without transplacental transfer.

Common INCI Names on Packaging
Centella Asiatica ExtractMadecassosideAsiaticosideMadecassic AcidAsiatic Acid
Permitted Alternatives During Pregnancy
  • ✓Panthenol (Vitamin B5)
  • ✓Colloidal Oatmeal

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