Differin Adapalene Gel 0.1% Acne Treatment
First over-the-counter third-generation synthetic naphthoic acid retinoid that binds selectively to retinoic acid nuclear receptors beta and gamma to normalize follicular keratinization.
Contains actives (Retinoid (Vitamin A) (AVOID)) that are universally paused throughout pregnancy and lactation due to fetal safety considerations.
Contains zero lipid esters or fatty acid chains that feed Malassezia yeast.
Texture: Clear Aqueous Gel Suspension. Apply strictly in order of thinnest water to thickest cream.
1 Actives • 7 Functional • 0 Watchlist
Layering Protocol: What NOT to Mix With This Bottle
- ✕AHA / BHA Direct Acids (especially during 4-week retinization phase)
- ✕Benzoyl Peroxide (unless skin is seasoned)
- ✓Ceramide PM Creams (sandwich layering)
- ✓Hyaluronic Acid
Full INCI Ingredient Declaration
Decoded using Miko's pharmacological database (8 ingredients detected).
Gold standard active for accelerating keratinocyte renewal, promoting dermal collagen I and III synthesis, and clearing follicular congestion.
Synthetic or fermentation-derived thickener that gives serums and gels their characteristic slip and prevents formula separation.
Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.
Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.
Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.
Multifunctional diol that dissolves active ingredients, improves spreadability, and acts as a lightweight humectant.
Deionized, ultra-purified solvent that serves as the delivery vehicle for hydrophilic actives and humectants.
Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.
Have Adapalene Gel 0.1% Acne Treatment on Your Bathroom Shelf?
Point your iPhone camera at this bottle and the rest of your cabinet. Miko reads physical packaging via on-device OCR, alerts you to active clashes, and sequences your weekly 7-day routine from what you already own.