La Roche-PosaytreatmentpH 5.0 – 5.5 • $22.99 (40ml)

La Roche-Posay Effaclar Duo+ M Anti-Blemish Treatment

Multi-targeted acne and post-inflammatory erythema treatment combining Niacinamide, Lipohydroxy Acid (Capryloyl Salicylic Acid), Salicylic Acid, Zinc PCA, and patented Phylobioma postbiotic extract targeting Cutibacterium acnes phylotype IA1.

Obstetric SafetyConcentration Dependent

Contains concentration-dependent ingredients (Salicylic Acid (BHA) (WATCH)). Rinse-off formulations are often cleared by OB-GYNs, while leave-ons should be verified.

Always confirm with your OB-GYN.
Malassezia (Fungal Acne)⚠ Triggers Detected

Contains lipid triggers: Polysorbate 80.

Safe for pityrosporum folliculitis? No
Viscosity Application OrderStep 4 of 7 • AM

Texture: Lightweight mattifying gel-cream with rapid absorption. Apply strictly in order of thinnest water to thickest cream.

pH: 5.0 – 5.5
Formulation BalancePotent / Active-Heavy

4 Actives • 30 Functional • 1 Watchlist

35 Total Ingredients

Layering Protocol: What NOT to Mix With This Bottle

Avoid Concurrent Application With:
  • ✕retinol
Recommended Synergistic Pairings:
  • ✓ceramides
  • ✓hyaluronic-acid
Want to test this bottle with another specific product on your shelf?Open Active Conflict Matrix→

Full INCI Ingredient Declaration

Decoded using Miko's pharmacological database (35 ingredients detected).

Zero Chemophobia • Evidence-Based
Purified Water (Aqua)(Aqua / Water / Eau)Base & Solvent

Deionized, ultra-purified solvent that serves as the delivery vehicle for hydrophilic actives and humectants.

neutralPore: 0/5
GlycerinHumectant

Master humectant that coordinates with cutaneous aquaporin-3 channels to maintain physiological stratum corneum hydration and plasticity.

goodPore: 0/5
Silicone (Dimethicone / Cyclopentasiloxane)(Dimethicone)Emulsifier & Texture

Large-chain polymer that forms a breathable, non-comedogenic mesh over the epidermis to prevent moisture evaporation without clogging pores.

neutralPore: 1/5
Isocetyl StearateBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Niacinamide (Vitamin B3)(Niacinamide)Active

Essential precursor to NAD+/NADP+ energy cofactors. Enhances skin lipid synthesis, decreases sebum excretion rate, and inhibits pigment transfer.

goodPore: 0/5
Isopropyl Lauroyl SarcosinateBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
SilicaBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Ammonium Polyacryloyldimethyl TaurateBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Oryza Sativa Starch / Rice StarchBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Punica Granatum Pericarp ExtractBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Potassium Cetyl PhosphateBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Sorbitan OleateBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Zinc PCABase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Glyceryl Stearate SEBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
IsohexadecaneBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Sodium HydroxideBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Myristyl MyristateBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
2-Oleamido-1Base & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
3-OctadecanediolBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
MannoseBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Poloxamer 338Base & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Glycol / Propanediol Solvent(Propanediol)Base & Solvent

Multifunctional diol that dissolves active ingredients, improves spreadability, and acts as a lightweight humectant.

neutralPore: 0/5
Hydroxyphenoxy Propionic AcidBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Salicylic Acid (BHA)(Capryloyl Salicylic Acid)Exfoliant

Oil-soluble beta hydroxy acid that selectively dissolves intracellular lipid bonds inside sebaceous ducts to clear microcomedones.

goodPore: 0/5
Broad-Spectrum Preservative System(Caprylyl Glycol)Preservative & Chelator

Essential preservation agent preventing dangerous Pseudomonas, Staphylococcus, and mold growth in aqueous skincare formulations.

neutralPore: 0/5
Vitreoscilla FermentBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Citric AcidBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Trisodium Ethylenediamine DisuccinateBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
MaltodextrinBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Rheology Modifier / Gelling Agent(Xanthan Gum)Emulsifier & Texture

Synthetic or fermentation-derived thickener that gives serums and gels their characteristic slip and prevents formula separation.

neutralPore: 0/5
Polysorbate (Emulsifier)(Polysorbate 80)Emulsifier & Texture

Standard cosmetic solubilizer. Chemically contains fatty acid chains that feed Malassezia yeast in fungal-acne-prone profiles.

neutralPore: 1/5
Acrylamide/Sodium Acryloyldimethyltaurate CopolymerBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Salicylic Acid (BHA)(Salicylic Acid)Exfoliant

Oil-soluble beta hydroxy acid that selectively dissolves intracellular lipid bonds inside sebaceous ducts to clear microcomedones.

goodPore: 0/5
Piroctone OlamineBase & Solvent

Formulation ingredient (emollient, binder, or botanical solvent) standard in cosmetic formulations.

neutralPore: 0/5
Fragrance (Synthetic Parfum Blend)(Parfum / Fragrance)Fragrance & Allergen

Undisclosed proprietary aromatic blend tracked as a leading contributor to type IV delayed allergic contact dermatitis.

watchPore: 0/5
iPhone App • No Account Required

Have Effaclar Duo+ M Anti-Blemish Treatment on Your Bathroom Shelf?

Point your iPhone camera at this bottle and the rest of your cabinet. Miko reads physical packaging via on-device OCR, alerts you to active clashes, and sequences your weekly 7-day routine from what you already own.

Download on theApp Store
$9.99/mo or $49.99/yr • 7-day free trial included