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Cell Turnover / RetinoidsRecommended: PM Slot

Adapalene

Clinical Overview

A photostable, lipophilic third-generation naphthoic acid retinoid engineered specifically for follicular comedolytic targeting.

Epidermal & Cutaneous Mechanism

Selectively binds nuclear RAR-beta and RAR-gamma with high affinity while showing zero degradation under UV light or benzoyl peroxide exposure.

Addresses Skin Concerns
Comedonal acneFollicular hyperkeratosisPost-acne texture
Recognized INCI Names on Packaging Labels
AdapaleneDifferin
Compatible Synergies
  • ✓Benzoyl Peroxide (specifically compatible with adapalene)
  • ✓Barrier Moisturizers
Separate or Alternate
  • ⚠️High-percentage Glycolic Acid peels

Layering Rules & Life-State Compatibility