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Permitted · Barrier & Sebum Regulator
Can you use Niacinamide (Vitamin B3) during pregnancy?
⚠️Medical Deferral Notice
Considered safe throughout pregnancy and lactation. Excellent for gestational barrier defense. Cosmetic classifications are formulation flags to discuss with your healthcare provider, not medical clearance.
Clinical Summary
A biocompatible B-vitamin that stimulates ceramide synthesis, regulates oil production, and fades hyperpigmentation.
Pharmacological Mechanism & Teratogenic Context
Niacinamide is the precursor to cellular coenzymes NAD(P) and NAD(P)H, vital for ATP production and DNA repair. Applied topically at 2%–5%, it inhibits melanosome transfer by 35%–68% and enhances epidermal barrier lipids without systemic risk.
Common INCI Names on Packaging
NiacinamideNicotinamide
Permitted Alternatives During Pregnancy
- ✓Panthenol (Vitamin B5)
- ✓Centella Asiatica